Provigil is a regulated drug given for people that have sleep disorders. Medically speaking, the generic name is called modafinil. The mechanism of action of the drug is that it increases the release of monoamines particularly catecholamines norepinephrine and dopamine from the synaptic terminals resulting in an increased wakefulness. If the drug is taken at therapeutic levels it automatically improves alertness and improves mental acuity. The drug has been approved for use in patients that are suffering from narcolepsy, which is a form of sleeping disorder where sufferers experience excessive daytime sleepiness usually within 3 to 4 hours each day.
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Indications for use
An indication for the use of Provigil is in obstructive sleep apnea, where sufferers have a decrease in air flowing through the airways while sleeping, causing irregular breathing patterns. This drug improves wakefulness in these patients as well. Another condition that this medication is used for is shift-work sleep disorder. This is an occupational condition where patients suffer from disrupted sleep cycles because they have varied night and morning shifts due to work.
There has also been some promise for the use of Provigil in the treatment of excessive daytime sleepiness in patients suffering from Parkinson’s disease. This is according to research from the journal of clinical neuropharmacology. Parkinson’s patients suffer from increased tremors at rest and this may be a cause of insomnia during the night as they are unable to maintain their sleep.
Another area where Provigil is gaining a lot of ground is in the weight loss category. While there is no clear cut evidence to say that the drug causes weight loss, it has been observed that patients that take the medication have reduced food intake or appetite, but since the medication is not an amphetamine, it should not cause an increase in heart rate.
Breakthrough Drug For Jet Lag
The drug is also gaining ground as an effective treatment for people that are suffering from jet lag. This condition is caused by the difference in time zones as passengers travel from one part of the world to the next. There is also some promise that Provigil may be used in the treatment of attention deficit disorder and depression.
Other Indications
Since Provigil increases mental acuity and alertness, the drug is also prescribed to individuals that are suffering from a cognitive decline. There is also some promise that Provigil may also be used in people suffering from social anxiety disorder or social phobia. Health care professionals need not be reminded of the potential for abuse of this medication. Physicians should be wary if patients are taking more than the prescribed dose or are taking it for something else other than the indication it was prescribed.